Almost everybody uses drugs active on the brain, and altering of emotions, arousal, energy and other brain functions.
Some people take all kinds of drugs, including those known to be harmful - the drug users/ abusers who take opiates, stimulants, downers, psychedelics and so on.
Many people take prescribed psychiatric drugs, more and more people - especially over the whole course of their lives.
Those who are skeptical or hostile towards prescribed psychiatric drugs almost always use non-prescribed drugs such a caffeine, alcohol or nicotine.
Those hostile to any or all of caffeine, alcohol or nicotine will almost always take prescribed psychiatric drugs when advised to.
And some take other herbal or herbally-derived psychoactive drugs such as Ginseng, St John's Wort etc
Who is left after subtracting all these groups? Very few - I don't think I have ever met such a person.
Essentially everybody uses psychoactive drugs. For the overwhelming majority, it is not a question of whether to use such drugs, but a choice of which drugs, at what dose and frequency.
Everybody need to know about psychopharmacology.