It occurs to me that the purpose of the industrial revolution was to prepare the way for a mass of souls that couldn't survive in a pre-industrial revolution world.
The modern social/sexual dysfunction should be seen as part of the nature of these souls, and not as some sort of addition to them surrounding but not bound-up with their nature.
The system of incarnation ceases to function, but this is just a practical issue - their mal/anti-adaptiveness is merely an interpretation from biology of what's actually their nature (from before incarnation).
So the mutation accumulation situation was actually intended as part of the plan of salvation - the mutation allows for the incarnation of these modern people.
The industrial revolution both allows for their incarnation, and provides for them once they're born, so they can go through mortal life.
Idea from regular commenter ben